Publikationen

ADAM10-Mediated Ectodomain Shedding Is an Essential Driver of Podocyte Damage
Sachs M, Wetzel S, Reichelt J, Sachs W, Schebsdat L, Zielinski S, Seipold L, Heintz L, Müller SA, Kretz O, Lindenmeyer M, Wiech T, Huber TB, Lüllmann-Rauch R, Lichtenthaler SF, Saftig P, Meyer-Schwesinger C.
J Am Soc Nephrol. 2021 Mar
 
SRGAP1 Controls Small Rho GTPases To Regulate Podocyte Foot Process Maintenance
Rogg M, Maier JI, Dotzauer R, Artelt N, Kretz O, Helmstädter M, Abed A, Sammarco A, Sigle A, Sellung D, Dinse P, Reiche K, Yasuda-Yamahara M, Biniossek ML, Walz G, Werner M, Endlich N, Schilling O, Huber TB, Schell C. 
J Am Soc Nephrol. 2021 Mar
 
Clonal expansion and activation of tissue-resident memory-like Th17 cells expressing GM-CSF in the lungs of severe COVID-19 patients
Zhao Y, Kilian C, Turner JE, Bosurgi L, Roedl K, Bartsch P, Gnirck AC, Cortesi F, Schultheiß C, Hellmig M, Enk LUB, Hausmann F, Borchers A, Wong MN, Paust HJ, Siracusa F, Scheibel N, Herrmann M, Rosati E, Bacher P, Kylies D, Jarczak D, Lütgehetmann M, Pfefferle S, Steurer S, Zur-Wiesch JS, Puelles VG, Sperhake JP, Addo MM, Lohse AW, Binder M, Huber S, Huber TB, Kluge S, Bonn S, Panzer U, Gagliani N, Krebs CF
Sci Immunol. 2021 Feb
 
The proteomic landscape of small urinary extracellular vesicles during kidney transplantation
Braun F, Rinschen M, Buchner D, Bohl K, Plagmann I, Bachurski D, Richard Späth M, Antczak P, Göbel H, Klein C, Lackmann JW, Kretz O, Puelles VG, Wahba R, Hallek M, Schermer B, Benzing T, Huber TB, Beyer A, Stippel D, Kurschat CE, Müller RU. 
J Extracell Vesicles. 2020 Oct
 
Amphiregulin Aggravates Glomerulonephritis via Recruitment and Activation of Myeloid Cells

Melderis S, Hagenstein J, Warkotsch MT, Dang J, Herrnstadt GR, Niehus CB, Neumann K, Panzer U, Berasain C, Avila MA, Tharaux PL, Tiegs G, Steinmetz OM.
J Am Soc Nephrol. 2020 Sep

Interleukin-9 protects from early podocyte injury and progressive glomerulosclerosis in Adriamycin-induced nephropathy.

Xiong T, Attar M, Gnirck AC, Wunderlich M, Becker M, Rickassel C, Puelles VG, Meyer-Schwesinger C, Wiech T, Nies JF, Divivier M, Fuchs T, Schulze Zur Wiesch J, Taipaleenmäki H, Hoxha E, Wirtz S, Huber TB, Panzer U, Turner JE.
Kidney Int. 2020 Sep

SARS-CoV-2 renal tropism associates with acute kidney injury

Braun F, Luetgehetmann M, Pferfferle S, Wong M, Carsten A, Lindenmeyer M, Noerz, D, Heinrich F, Meißner K, Wichmann D, Kluge S, Gross O, Pueschel K, Schroeder AS, Edler C, Aepfelbacher M, Puelles V, Huber TB.
The Lancet. 2020 Aug

Pathogen-induced tissue-resident memory TH17 (TRM17) cells amplify autoimmune kidney disease.
Krebs CF, Reimers D, Zhao Y, Paust HJ, Bartsch P, Nuñez S, Rosemblatt MV, Hellmig M, Kilian C, Borchers A, Enk LUB, Zinke M, Becker M, Schmid J, Klinge S, Wong MN, Puelles VG, Schmidt C, Bertram T, Stumpf N, Hoxha E, Meyer-Schwesinger C, Lindenmeyer MT, Cohen CD, Rink M, Kurts C, Franzenburg S, Koch-Nolte F, Turner JE, Riedel JH, Huber S, Gagliani N, Huber TB, Wiech T, Rohde H, Bono MR, Bonn S, Panzer U, Mittrücker HW.
Sci Immunol. 2020 Aug
 
Distinct modes of balancing glomerular cell proteostasis in mucolipidosis type II and III prevent proteinuria.

Sachs W, Sachs M, Krüger E, Zielinski S, Kretz, Huber TB, Baranowsky A, Westermann LM, Volontolini Velho R, Ludwig NF, Yorgan TA, Di Lorenzo G, Kollmann K, Braulke T, Schwartz IV, Schinke T, Danyukova T, Pohl S, Meyer-Schwesinger C.
J Am Soc Nephrol. 2020 Aug

Neural metabolic imbalance induced by MOF dysfunction triggers pericyte activation and breakdown of vasculature.

Sheikh BN, Guhathakurta S, Tsang TH, Schwabenland M, Renschler G, Herquel B, Bhardwaj V, Holz H, Stehle T, Bondareva O, Aizarani N, Mossad O, Kretz O, Reichardt W, Chatterjee A, Braun LJ, Thevenon J, Sartelet H, Blank T, Grün D, von Elverfeldt D, Huber TB, Vestweber D, Avilov S, Prinz M, Buescher JM, Akhtar A.
Nat Cell Biol. 2020 Jul

A reciprocal regulation of spermidine and autophagy in podocytes maintains the filtration barrier.

Liang W, Yamahara K, Hernando-Erhard C, Lagies S, Wanner N, Liang H, Schell C, Kammerer B, Huber TB, Bork T.
Kidney Int. 2020 Jun

Microbiota-Induced Type I Interferons Instruct a Poised Basal State of Dendritic Cells.

Schaupp L, Muth S, Rogell L, Kofoed-Branzk M, Melchior F, Lienenklaus S, Ganal-Vonarburg SC, Klein M, Guendel F, Hain T, Schütze K, Grundmann U, Schmitt V, Dorsch M, Spanier J, Larsen PK, Schwanz T, Jäckel S, Reinhardt C, Bopp T, Danckwardt S, Mahnke K, Heinz GA, Mashreghi MF, Durek P, Kalinke U, Kretz O, Huber TB, Weiss S, Wilhelm C, Macpherson AJ, Schild H, Diefenbach A, Probst HC.
Cell. 2020 May

Multi-organ and renal tropism of SARS-CoV-2

Puelles VG, Lütgehetmann M, Lindenmeyer MT, Sperhake JP, Wong MN, Allweiss L, Chilla S, Heinemann A, Nicola Wanner N, Liu S, Braun F, Lu S, Pfefferle S, Schröder AS, Edler C, Gross O, Glatzel M, Wichmann D, Wiech T, Stefan Kluge S, Pueschel K, Aepfelbacher M, Huber TB
New England Journal of Medicine. 2020 May

Drawing a single-cell landscape of the human kidney in (pseudo)-space and time.

Krebs CF, Schlitzer A, Kurts C.
Kidney Int. 2020 May

COVID-19-associated nephritis: early warning for disease severity and complications?

Gross O, Moerer O, Weber M, Huber TB, Scheithauer S
The Lancet. Published Online 2020 May

A novel mouse model of phospholipase A2 receptor 1-associated membranous nephropathy mimics podocyte injury in patients

Meyer-Schwesinger C, Tomas NM, Dehde S, Seifert L, Hermans-Borgmeyer I, Wiech T, Koch-Nolte F, Huber TB, Zahner G.
Kidney Int. 2020 May

B6.Rag1 Knockout Mice Generated at the Jackson Laboratory in 2009 Show a Robust Wild-Type Hypertensive Phenotype in Response to Ang II (Angiotensin II).

Seniuk A, Thiele JL, Stubbe A, Oser P, Rosendahl A, Bode M, Meyer-Schwesinger C, Wenzel UO, Ehmke H.
Hypertension. 2020 Apr

A high-salt diet compromises antibacterial neutrophil responses through hormonal perturbation.

Jobin K, Stumpf NE, Schwab S, Eichler M, Neubert P, Rauh M, Adamowski M, Babyak O, Hinze D, Sivalingam S, Weisheit C, Hochheiser K, Schmidt SV, Meissner M, Garbi N, Abdullah Z, Wenzel U, Hölzel M, Jantsch J, Kurts C
Sci Transl Med. 2020 Mar

CFHR Gene Variations Provide Insights in the Pathogenesis of the Kidney Diseases Atypical Hemolytic Uremic Syndrome and C3 Glomerulopathy.

Zipfel PF, Wiech T, Stea ED, Skerka C.
J Am Soc Nephrol. 2020 Feb

IL-17C/IL-17RE: Emergence of a Unique Axis in TH17 Biology.

Nies JF, Panzer U
Front Immunol. 2020 Feb

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