Publications
Pathology-oriented multiplexing enables integrative disease mapping
Kuehl M, Okabayashi Y, Wong MN, Gernhold L, Gut G, Kaiser N, Schwerk M, Gräfe SK, Ma FY, Tanevski J, Schäfer PSL, Mezher S, Sarabia Del Castillo J, Goldbeck-Strieder T, Zolotareva O, Hartung M, Delgado Chaves FM, Klinkert L, Gnirck AC, Spehr M, Fleck D, Joodaki M, Parra V, Shaigan M, Diebold M, Prinz M, Kranz J, Kux JM, Braun F, Kretz O, Wu H, Grahammer F, Heins S, Zimmermann M, Haas F, Kylies D, Wanner N, Czogalla J, Dumoulin B, Zolotarev N, Lindenmeyer M, Karlson P, Nyengaard JR, Sebode M, Weidemann S, Wiech T, Groene HJ, Tomas NM, Meyer-Schwesinger C, Kuppe C, Kramann R, Karras A, Bruneval P, Tharaux PL, Pastene D, Yard B, Schaub JA, McCown PJ, Pyle L, Choi YJ, Yokoo T, Baumbach J, Sáez PJ, Costa I, Turner JE, Hodgin JB, Saez-Rodriguez J, Huber TB, Bjornstad P, Kretzler M, Lenoir O, Nikolic-Paterson DJ, Pelkmans L, Bonn S, Puelles VG.
Nature. 2025 Jul
Anti-nephrin autoantibodies in steroid-resistant nephrotic syndrome may inform treatment strategy.
Hengel FE, Dehde S, Yilmaz A, Bayasit AK, Ozaltin F, Paripovic D, Emma F, Ronco P, Vivarelli M, Hogan J, Schaefer F, Tomas NM, Huber TB.
Kidney Int. 2025 Jun
Type I interferon drives T cell cytotoxicity by upregulation of interferon regulatory factor 7 in autoimmune kidney diseases in mice.
Wang H, Engesser J, Khatri R, Schaub DP, Paust HJ, Sultana Z, Jauch-Speer SL,
Peters A, Kaffke A, Bonn S, Huber TB, Mittrücker HW, Krebs CF, Panzer U, Asada
N.
Nat Commun. 2025 May
Immunohistochemical and serological characterization of membranous nephropathy in children and adolescents.
Dettmar AK, Wiech T, Kemper MJ, Soave A, Rink M, Oh J, Stahl RAK, Hoxha E.
Pediatr Nephrol. 2018 Mar
Scaffold polarity proteins Par3A and Par3B share redundant functions while Par3B acts independent of atypical protein kinase C/Par6 in podocytes to maintain the kidney filtration barrier.
Koehler S, Odenthal J, Ludwig V, Jess DU, Höhne M, Jüngst C, Grawe F, Helmstädter M, Janku JL, Bergmann C, Hoyer PF, Hagmann HHH, Walz G, Bloch W, Niessen C, Schermer B, Wodarz A, Denholm B, Benzing T, Iden S, Brinkkoetter PT.
Kidney Int. 2021 Dec
Non-invasive diagnosis of anti-nephrin–associated podocytopathy.
Hengel FE, Chong MCZ, Leung WY, Dehde S, Mühlig A, Janneck M, Wu HHL, Huber TB, Ponnusamy A, Tomas NM.
Kidney Int Rep. 2025 May
ATP-Gated P2X7-Ion Channel on Kidney-Resident Natural Killer T Cells and Memory T Cells in Intrarenal Inflammation.
Marten Junge, Nastassia Liaukouskaya, Nicole Schwarz, Carolina Pinto-Espinoza, Alessa Z Schaffrath, Björn Rissiek, Christian F Krebs, Guido Rattay, Hans-Willi Mittrücker, Nicola M Tomas, Annette Nicke, Friedrich Haag, Tobias B Huber, Catherine Meyer-Schwesinger, Friedrich Koch-Nolte, Nicola Wanner.
JASN. 2025 Apr
The integrated stress response pathway controls cytokine production in tissue-resident memory CD4+ T cells.
Asada N, Ginsberg P, Paust HJ, Song N, Riedel JH, Turner JE, Peters A, Kaffke A, Engesser J, Wang H, Zhao Y, Khatri R, Gild P, Dahlem R, Diercks BP, Das S, Ignatova Z, Huber TB, Prinz I, Gagliani N, Mittrücker HW, Krebs CF, Panzer U.
Nat Immunol. 2025 Apr
Potential and pitfalls of measuring circulating anti-nephrin autoantibodies in glomerular diseases.
Hengel FE, Huber TB, Tomas NM.
Clin Kidney J. 2025 Apr
Passive transfer of patient-derived anti-nephrin autoantibodies causes a podocytopathy with minimal change lesions.
Hengel FE, Dehde S, Kretz O, Engesser J, Zimmermann T, Huber TB*, Tomas NM.
J Clin Invest. 2025 Jan