A Mechanism for Cancer-Associated Membranous Nephropathy.
Hoxha E, Wiech T, Stahl PR, Zahner G, Tomas NM, Meyer-Schwesinger C, Wenzel U, Janneck M, Steinmetz OM, Panzer U, Harendza S, Stahl RA
N Engl J Med. 2016 May
A novel mouse model of phospholipase A2 receptor 1-associated membranous nephropathy mimics podocyte injury in patients
Kidney Int. 2020 May
* contributed equally
A novel mouse model of phospholipase A2 receptor 1-associated membranous nephropathy mimics podocyte injury in patients.
Catherine Meyer-Schwesinger, Nicola M Tomas, Silke Dehde, Larissa Seifert, Irm Hermans-Borgmeyer, Thorsten Wiech, Friedrich Koch-Nolte, Tobias B Huber, Gunther Zahner
Kidney Int. 2020 May
Across scales: novel insights into kidney health and disease by structural biology.
Nicola M Tomas, Simon A Mortensen, Matthias Wilmanns, Tobias B Huber
Kidney Int. 2021 Apr
Anti-nephrin autoantibodies in steroid-resistant nephrotic syndrome may inform treatment strategy.
Hengel FE, Dehde S, Yilmaz A, Bayasit AK, Ozaltin F, Paripovic D, Emma F, Ronco P, Vivarelli M, Hogan J, Schaefer F, Tomas NM, Huber TB.
Kidney Int. 2025 Jun
ATP-Gated P2X7-Ion Channel on Kidney-Resident Natural Killer T Cells and Memory T Cells in Intrarenal Inflammation.
Marten Junge, Nastassia Liaukouskaya, Nicole Schwarz, Carolina Pinto-Espinoza, Alessa Z Schaffrath, Björn Rissiek, Christian F Krebs, Guido Rattay, Hans-Willi Mittrücker, Nicola M Tomas, Annette Nicke, Friedrich Haag, Tobias B Huber, Catherine Meyer-Schwesinger, Friedrich Koch-Nolte, Nicola Wanner. JASN. 2025 Apr
Autoantibodies Targeting Nephrin in Podocytopathies.
Hengel FE, Dehde S, Lassé M, Zahner G, Seifert L, Schnarre A, Kretz O, Demir F, Pinnschmidt HO, Grahammer F, Lucas R, Mehner LM, Zimmermann T, Billing AM, Oh J, Mitrotti A, Pontrelli P, Debiec H, Dossier C, Colucci M, Emma F, Smoyer WE, Weins A, Schaefer F, Alachkar N, Diemert A, Hogan J, Hoxha E, Wiech T, Rinschen MM, Ronco P, Vivarelli M, Gesualdo L, Tomas NM, Huber TB.
N Engl J Med. 2024 Aug
Autoantibodies Targeting Nephrin in Podocytopathies.
Hengel FE, Dehde S, Lassé M, Zahner G, Seifert L, Schnarre A, Kretz O, Demir F, Pinnschmidt HO, Grahammer F, Lucas R, Mehner LM, Zimmermann T, Billing AM, Oh J, Mitrotti A, Pontrelli P, Debiec H, Dossier C, Colucci M, Emma F, Smoyer WE, Weins A, Schaefer F, Alachkar N, Diemert A, Hogan J, Hoxha E, Wiech T, Rinschen MM, Ronco P, Vivarelli M, Gesualdo L, Tomas NM, Huber TB.
N Engl J Med. 2024 Aug
Non-invasive diagnosis of anti-nephrin–associated podocytopathy.
Hengel FE, Chong MCZ, Leung WY, Dehde S, Mühlig A, Janneck M, Wu HHL, Huber TB, Ponnusamy A, Tomas NM.
Kidney Int Rep. 2025 May
Passive transfer of patient-derived anti-nephrin autoantibodies causes a podocytopathy with minimal change lesions.
Felicitas E. Hengel, Silke Dehde, Oliver Kretz, Jonas Engesser, Tom Zimmermann, Tobias B. Huber, Nicola M. Tomas.
J Clin Invest. 2025 Jan
Passive transfer of patient-derived anti-nephrin autoantibodies causes a podocytopathy with minimal change lesions.
Hengel FE, Dehde S, Kretz O, Engesser J, Zimmermann T, Huber TB*, Tomas NM.
J Clin Invest. 2025 Jan
Perspectives in membranous nephropathy
Tomas NM, Huber TB, Hoxha E.
Cell Tissue Res. 2021 Apr
Podocyte expression of human phospholipase A2 receptor 1 causes immune-mediated membranous nephropathy in mice.
Nicola M Tomas, Silke Dehde, Catherine Meyer-Schwesinger, Ming Huang, Irm Hermans-Borgmeyer, Johanna Maybaum, Renke Lucas, Jennie L von der Heide, Oliver Kretz, Sarah M S Köllner, Larissa Seifert, Tobias B Huber, Gunther Zahner
Kidney int. 2023 Feb
Potential and pitfalls of measuring circulating anti-nephrin autoantibodies in glomerular diseases.
Hengel FE, Huber TB, Tomas NM.
Clin Kidney J. 2025 Apr
The classical pathway triggers pathogenic complement activation in membranous nephropathy.
Larissa Seifert, Gunther Zahner, Catherine Meyer-Schwesinger, Naemi Hickstein, Silke Dehde, Sonia Wulf, Sarah M S Köllner, Renke Lucas, Dominik Kylies, Sarah Froembling, Stephanie Zielinski, Oliver Kretz, Anna Borodovsky, Sergey Biniaminov, Yanyan Wang, Hong Cheng, Friedrich Koch-Nolte, Peter F Zipfel, Helmut Hopfer, Victor G Puelles, Ulf Panzer, Tobias B Huber, Thorsten Wiech, Nicola M Tomas
Nat Commun. 2023 Jan
The classical pathway triggers pathogenic complement activation in membranous nephropathy.
Larissa Seifert, Gunther Zahner, Catherine Meyer-Schwesinger, Naemi Hickstein, Silke Dehde, Sonia Wulf, Sarah M S Köllner, Renke Lucas, Dominik Kylies, Sarah Froembling, Stephanie Zielinski, Oliver Kretz, Anna Borodovsky, Sergey Biniaminov, Yanyan Wang, Hong Cheng, Friedrich Koch-Nolte, Peter F Zipfel, Helmut Hopfer, Victor G Puelles, Ulf Panzer, Tobias B Huber, Thorsten Wiech, Nicola M Tomas.
Nat Commun. 2023 Jan