SFB 1192

Dr. rer. nat. Sonja Hiekmann

Projekt A1

Post-Doc
III. Medizinische Klinik, UKE
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Wissenschaftliche Karriere
  • Ph.D. im Rahmen des „International PhD program in Basic and Applied Molecular Life Sciences“
  • Titel der Doktorarbeit: „Probing Atypical Chemokine Biology“, Université de Genève, Schweiz
  • Studium der Biologie - Zellbiologie, Christian-Albrechts-Universität zu Kiel, Deutschland
Publikationen

IL-17C/IL-17 Receptor E Signaling in CD4+ T Cells Promotes TH17 Cell-Driven Glomerular Inflammation.
Krohn S, Nies JF, Kapffer S, Schmidt T, Riedel JH, Kaffke A, Peters A, Borchers A, Steinmetz OM, Krebs CF, Turner JE, Brix SR, Paust HJ, Stahl RAK, Panzer U.
J Am Soc Nephrol. 2018 Apr

IL-33-Mediated Expansion of Type 2 Innate Lymphoid Cells Protects from Progressive Glomerulosclerosis.
Riedel JH, Becker M, Kopp K, Düster M, Brix SR, Meyer-Schwesinger C, Kluth LA, Gnirck AC, Attar M, Krohn S, Fehse B, Stahl RAK, Panzer U, Turner JE.
J Am Soc Nephrol. 2017 Jul

Autoimmune Renal Disease Is Exacerbated by S1P-Receptor-1-Dependent Intestinal Th17 Cell Migration to the Kidney.
Krebs CF, Paust HJ, Krohn S, Koyro T, Brix SR, Riedel JH, Bartsch P, Wiech T, Meyer-Schwesinger C, Huang J, Fischer N, Busch P, Mittrücker HW, Steinhoff U, Stockinger B, Perez LG, Wenzel UO, Janneck M, Steinmetz OM, Gagliani N, Stahl RAK, Huber S, Turner JE, Panzer U.
Immunity. 2016 Nov

Plasticity of Th17 Cells in Autoimmune Kidney Diseases.
Krebs CF, Turner JE, Paust HJ, Kapffer S, Koyro T, Krohn S, Ufer F, Friese MA, Flavell RA, Stockinger B, Steinmetz OM, Stahl RA, Huber S, Panzer U.
J Immunol. 2016 Jul

IL-17F Promotes Tissue Injury in Autoimmune Kidney Diseases.
Riedel JH, Paust HJ, Krohn S, Turner JE, Kluger MA, Steinmetz OM, Krebs CF, Stahl RA, Panzer U.
J Am Soc Nephrol. 2016 Dec

CXCR3+ Regulatory T Cells Control TH1 Responses in Crescentic GN.
Paust HJ, Riedel JH, Krebs CF, Turner JE, Brix SR, Krohn S, Velden J, Wiech T, Kaffke A, Peters A, Bennstein SB, Kapffer S, Meyer-Schwesinger C, Wegscheid C, Tiegs G, Thaiss F, Mittrücker HW, Steinmetz OM, Stahl RA, Panzer U.
J Am Soc Nephrol. 2016 Jul

CC Chemokine Ligand 18 in ANCA-Associated Crescentic GN.
Brix SR, Stege G, Disteldorf E, Hoxha E, Krebs C, Krohn S, Otto B, Klätschke K, Herden E, Heymann F, Lira SA, Tacke F, Wolf G, Busch M, Jabs WJ, Özcan F, Keller F, Beige J, Wagner K, Helmchen U, Noriega M, Wiech T, Panzer U, Stahl RA.
J Am Soc Nephrol. 2015 Sep

Chemokine receptor antagonist development.
Garin, A., Z. Johnson, A. Hermant, F. Beltran, Y. Ratinaud, A. Michel, S. Krohn, M. Gaudet, S. Carboni, H. Ji, M. Missotten, O. Leger, C. Power and A.E.I. Proudfoot.
Methods Mol Biol. 2013

The activity of CCL18 is principally mediated through interaction with glycosaminoglycans.
Krohn, S., A. Garin, C. Gabay and A.E.I. Proudfoot.
Front Immunol. 2013 Jul

Evasin-4, a tick-derived chemokine binding protein with broad selectivity can be modified for use in pre-clinical disease models.
Déruaz M., P. Bonvin, I.C. Severin, Z. Johnson, S. Krohn, C.A. Power and A.E.I. Proudfoot.
FEBS J. 2013 Aug

CCL18 exhibits a regulatory role through inhibition of receptor and glycosaminoglycan binding.
Krohn, S., P. Bonvin and A.E.I. Proudfoot.
PlosOne. 2013 Aug

III. Medizinische Klinik und Poliklinik
Universitätsklinikum Hamburg-Eppendorf

Martinistrasse 52
20246 Hamburg, Germany
Tel:   +49-40-7410-51557
Fax:  +49-40-7410-59036
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